Relationships between Regional Radiation Doses and Cognitive Decline in Children Treated with Cranio-Spinal Irradiation for Posterior Fossa Tumors
Pediatric posterior fossa tumor (PFT) survivors who have been treated with cranial radiation therapy often suffer from cognitive impairments that might relate to IQ decline.Radiotherapy (RT) distinctly affects brain regions involved in different cognitive functions.However, the relative contribution of regional irradiation to the different cognitiv